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Home > Products >  Tacrolimus

Tacrolimus CAS NO.104987-11-3

  • Min.Order: 10 Gram
  • Payment Terms: T/T,Other
  • Product Details

Keywords

  • Tacrolimus
  • antibiotic
  • Cardarine

Quick Details

  • ProName: Tacrolimus
  • CasNo: 104987-11-3
  • Molecular Formula: C30H48O3
  • Appearance: White or white crystalline powder
  • Application: Burning fat, growing muscle
  • DeliveryTime: 3-7 days after payment
  • PackAge: As your request
  • Port: Shanghai;Shenzhen;Guangzhou;Wuhan;USA;...
  • ProductionCapacity: 500 Kilogram/Week
  • Purity: 99%
  • Storage: cool,avoid light and dry place,
  • Transportation: By sea,air,express
  • LimitNum: 10 Gram
  • Moisture Content: ISO 9000
  • Impurity: 99%
  • Belong to: Sarms
  • Application: Muscle building
  • Appearance: white crytalline powder
  • Skype: huxin90
  • whatsapp: +8613545168209
  • Wechat: hx395673863
  • E-mail: janney@ycphar.com

Superiority

 

1. Rich experience.

Our company is a professional manufacturer leading in China in pharmaceutical area .We specialize in this field for 19 years. Our steroids and pharmaceutical raw materials have been exported to the whole world.We have got very good feedback from our customers, and established long friendly relations of cooperation.

2. Great quality, purity and favorable.

Our products are after repeated extraction, multiple detection,good quality is one secret for our success. Welcome order the samples, MOQ just 10 grams.

3. Safest and fastest delivery.

Safe and professional disguised package can be guaranteed.We have adequate stock, we can arrange the delivery within 24hours when receiving the payment. 

Tracking number would be informed quickly after shipment.

We have special way which could ship 0.01 kilo to 50 kilo products a time.Provide door-to-door delivery.

4. Good after-sales service.

24/7 is available. Tell the package update info ASAP. And try our best to solve various problems customers encounter timely!

5. Experiential shopping

Besides raw steroid powder and liquid, we offer hormone solution and formula. We can teach you how to make hormone solution on the site.

We also provide semi-finished products, only need to filter by yourself, can be used as a finished product.

Details

CAS: 104987-11-3
MF: C44H69NO12
MW: 804.02
Product Categories:Pharmaceuticals;Chiral Reagents;Fujimycin, Prograf;antibiotic
Chemical Properties: White Crystalline Solid
Assay:99%
Usage: An immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release.
Packing:2g/foil bag

2.Product Description:

Tacrolimus  is an immunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection. It achieves this by inhibiting the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital to the body's learned (or adaptive) immune response. Tacrolimus is also used in the treatment of other T cell-mediated diseases such as eczema (for which it is applied to the skin in a medicated ointment), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, Kimura's disease, and the skin condition vitiligo.

3.Product Application:

Heart liver kidney and bone marrow transplant patients preferred immune-suppressing drugs after the transplant rejection resistant to conventional immunosuppressive regimen, is also the choice of the drug... Adverse reactions similar to cyclosporine. autoimmune eye disease and other autoimmune diseases also play an active role.

4.Function:

It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with tacrolimus was associated with a significantly lower rate of acute rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study. Clinical outcome is better with tacrolimus than with ciclosporin during the first year of liver transplantation. Long term outcome has not been improved to the same extent. Tacrolimus is normally prescribed as part of a post-transplant cocktail including steroids, mycophenolate and IL-2 receptor inhibitors. Dosages are titrated to target blood levels. Typical starting doses for once daily tacrolimus are 0.15-0.20 mg/kg body weight.
 
As an ointment, tacrolimus is used in the treatment of eczema, in particular atopic dermatitis. It suppresses inflammation in a similar way to steroids, and is equally as effective as a mid-potency steroid. An important advantage of tacrolimus is that, unlike steroids, it does not cause skin thinning (atrophy), or other steroid related side-effects.
 
It is applied on the active lesions until they heal off, but may also be used continuously in low doses (twice a week), and applied to the thinner skin over the face and eyelids[citation needed]. Clinical trials of up to one year have been conducted. Recently it has also been used to treat segmental vitiligo in children, especially in areas on the face

5.COA:
 
Tests Specifications Results
Description A white or off-white crystalline powder Conform
Identification 1. IR (USP <197K>) Conform
  2. HPLC retention times Conform
Water 
(USP <921> Method I)
1.6 ~ 3.0% 2.1%
Residue on ignition 
(USP <281>)
£ 0.2% 0.08%
Heavy metals 
(USP <231> II)
£ 20 ppm < 20 ppm
Related substances (In-house HPLC method) Ascomycin £ 0.8% 0.064%
Residual solvents 
(In-house method)
Acetone £ 2000 ppm Not detected
Assay (on anhydrous basis) 98.0% ~ 102.0% 100.0%
Conclusion: Complied with In-House standard
 
Anabolicum (LGD-4033) is unarguably the strongest SARM on the market today as far as anabolic power. It adds extra muscle building power to a cutting cycle, strength and size to a bulking cycle, and resilience for the endurance athlete. Used by itself or stacked with one or more other compounds, LGD demands recognition in the world of health, fitness, and bodybuilding.
 
How it works
 
LGD-4033, a novel nonsteroidal, oral selective androgen receptor modulator, binds to the androgen receptor with high affinity and selectivity. It demonstrates anabolic activity in muscles, anti-resorptive and anabolic activity in bones and a robust selectivity for muscle and bone versus prostate and sebaceous glands. LGD-4033 has recently completed a Phase I Multiple Ascending Dose study in healthy volunteers.  This randomized, double-blind, placebo-controlled Phase I study established the safety and tolerability up to doses of 22 mg per day.
 
LGD-4033 Benefits
 
Anabolicum (LGD), like other popular SARMS, is very versatile and has a list of benefits no matter the goal of the user. Whether it’s lean muscle mass, maintenance of your hard earned gains during a cutting cycle, or bridging the gap between steroid cycles, LGD-4033 can be a very beneficial tool. Studies suggest that this SARM will lend therapeutic benefit to many testosterone deficiency conditions. In fact, it’s not unheard of to hear of improvements in joint pain or nagging injuries after starting a course of Anabolicum (LGD), much like its cousin Ostarine (MK-2866). In addition, LGD can increase strength, vascularity, and fat loss while bulking, and it can help during “recomposition” (recomp).
 

 

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